{"id":6467,"date":"2025-01-28T10:58:16","date_gmt":"2025-01-28T08:58:16","guid":{"rendered":"https:\/\/foliush-igor.com\/vplyv-fazy-shvydkogo-snu-na-ryzyk-rozvytku-hvoroby-alczgejmera\/"},"modified":"2025-01-28T11:23:16","modified_gmt":"2025-01-28T09:23:16","slug":"the-impact-of-rem-sleep-on-the-risk-of-developing-alzheimer-s-disease","status":"publish","type":"post","link":"https:\/\/foliush-igor.com\/en\/the-impact-of-rem-sleep-on-the-risk-of-developing-alzheimer-s-disease\/","title":{"rendered":"The impact of REM sleep on the risk of developing Alzheimer&#8217;s disease"},"content":{"rendered":"<p><span data-preserver-spaces=\"true\">A recent <a href=\"https:\/\/www.sciencedaily.com\/releases\/2025\/01\/250127124458.htm\">study<\/a> suggests that delays in the REM (rapid eye movement) phase of sleep may serve as an early indicator of Alzheimer&#8217;s disease risk.<\/span><\/p>\n<figure id=\"attachment_4438\" aria-describedby=\"caption-attachment-4438\" style=\"width: 1200px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-4438\" src=\"https:\/\/foliush-igor.com\/wp-content\/uploads\/2024\/10\/1200-680-05-10-24-01.webp\" alt=\"\" width=\"1200\" height=\"680\" srcset=\"https:\/\/foliush-igor.com\/wp-content\/uploads\/2024\/10\/1200-680-05-10-24-01.webp 1200w, https:\/\/foliush-igor.com\/wp-content\/uploads\/2024\/10\/1200-680-05-10-24-01-768x435.webp 768w\" sizes=\"auto, (max-width: 1200px) 100vw, 1200px\" \/><figcaption id=\"caption-attachment-4438\" class=\"wp-caption-text\">by @freepik<\/figcaption><\/figure>\n<p><span data-preserver-spaces=\"true\">REM sleep, occurring after three stages of non-REM sleep, is critical for memory consolidation and learning. Dr Yue Leng from the University of California, San Francisco, explained, &#8220;Delayed REM sleep disrupts the brain&#8217;s ability to consolidate memories, interfering with the process that promotes learning and memory.&#8221; This delay elevates cortisol levels, a stress hormone that adversely affects the hippocampus, a brain region essential for retaining information.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">Published in <\/span><em><span data-preserver-spaces=\"true\">Alzheimer&#8217;s and Dementia: The Journal of the Alzheimer&#8217;s Association<\/span><\/em><span data-preserver-spaces=\"true\">, the study involved 128 participants with an average age of 70. Among them, half had Alzheimer&#8217;s disease, one-third had mild cognitive impairment, and the rest demonstrated normal cognitive function. By monitoring brain activity, eye movements, and other physiological markers overnight, researchers found a strong correlation between delayed REM sleep and elevated levels of toxic amyloid and tau proteins, hallmarks of Alzheimer&#8217;s disease. The study showed 16% higher amyloid, 29% higher tau, and 39% lower levels of brain-derived neurotrophic factor (BDNF), a key molecule for neuronal health, in individuals with delayed REM sleep.<\/span><\/p>\n<p><span data-preserver-spaces=\"true\">Potential interventions, such as melatonin and certain insomnia medications, have shown promise in animal studies, reducing tau and amyloid accumulation and improving REM sleep quality. <div class=\"su-quote su-quote-style-default\"><div class=\"su-quote-inner su-u-clearfix su-u-trim\">&#8220;Future studies should examine the effects of these drugs on disease progression in humans,&#8221; Dr. Leng stated.<\/div><\/div><\/span><\/p>\n<p><span data-preserver-spaces=\"true\">Doctors recommend maintaining healthy sleep habits, avoiding alcohol, and treating conditions like sleep apnea to lower Alzheimer&#8217;s risk. Additionally, Dr. Dantao Peng of the China-Japan Friendship Hospital in Beijing noted, <div class=\"su-quote su-quote-style-default\"><div class=\"su-quote-inner su-u-clearfix su-u-trim\">&#8220;Patients taking antidepressants or anti-anxiety medications should discuss with their doctor the possible impact of these drugs on REM sleep.&#8221;<\/div><\/div><\/span><\/p>\n<p><strong><span data-preserver-spaces=\"true\">Disclaimer:<\/span><\/strong><span data-preserver-spaces=\"true\"> Medical research statistics represent general trends and may not apply to everyone. Always consult a healthcare professional for personalized advice on your health.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent study suggests that delays in the REM (rapid eye movement) phase of sleep may serve as an early indicator of Alzheimer&#8217;s disease risk. REM sleep, occurring after three stages of non-REM sleep, is critical for memory consolidation and learning. Dr Yue Leng from the University of California, San Francisco, explained, &#8220;Delayed REM sleep [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":4439,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[152],"tags":[],"class_list":{"0":"post-6467","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-news-en"},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/posts\/6467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/comments?post=6467"}],"version-history":[{"count":0,"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/posts\/6467\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/media\/4439"}],"wp:attachment":[{"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/media?parent=6467"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/categories?post=6467"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/foliush-igor.com\/en\/wp-json\/wp\/v2\/tags?post=6467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}